羥丙基甲基纖維素的接枝改性、化學修飾及應用性能研究.pdf

1、天津大學博士學位論文羥丙基甲基纖維素的接枝改性、化學修飾及應用性能研究姓名：王麗麗申請學位級別：博士專業(yè)：應用化學指導教師：許湧深20061201ABSTRACTGraRcopoIyme血ationofethylac巧late(EA)ont0wate卜solublecellulosederiVatiVe—hydroxypropylmethylcellulose(Ⅲ’MC)、張scarried0utwithpotassiumpersulf

2、ate(KPS)asinitiatorinanaqueousmedi啪TheprocessofgraRcopolymerizationw嬲similartothatofclassicalemulsionpolymerization，whichcanbediVidedintotl玳estages：nucleation，gro砒，andpolymeriz亂ionfinishThee丑’ectsofmonomerconcen把ltion，in

3、itiatorconcen仃ation，matrixconcen仃iltion，reactiontemperatIlre，鋤dtheiIl仃oducingofthesecondfUnctionalmonomersiIlte衄softhepeI℃entageofgraRing(G)andgraRingefficiency(GE)wereinvestigatedTheintemctionsbe咐eenHPMCandKPSbeforetheg

4、raRcopolymerizationprocessinaqueollssystemwerealsoinvestigatedTheresultsshowthatthespeci矗cviscosit)rofHPMCsolutiondecreasessignmcantlywiulincreasingtheinteractiontime，andKPScanleadtotheoxidedegradationofthemainchainofHPM

5、CmacromoIeculesOntheotherhand，decompositionrateofKPSshowsfirstorderwithrespectt0theconcentrationofKPSinthepresenceofHPMC，whichisjustthes鋤easinpurewaterHoweVer，thedecompositionrateconstantofKPSinthepresenceofHPMCis7timesh

6、igherthanthatofinwaterat60℃Introducingthesecond如nctionalmonomer，dimethylaminoethylmethac巧late(DMAEMA)，into也e舒aftcopolymerizationcanmakethegraRcopolymersolubleinthesimulatedgastricfluidTheresistancemoistureabso印tionproper

7、哆increasesabout5timeswiththehi曲erGValuel5189％Thepotassiumchloride(KCl)slowreleasetabletispreparedbyusingthe伊aRcopolymerlatexasthebindingagentofthetabIet、ⅣbenGValuesare5929％，10067％andtheaddedamountislO％or20％，廿lereleasepro

8、pertiesofKCIslowreleasetabletssatis匆therequirementofChinapha鋤acopeiaInaddition，the伊aRcopolymersobtainedwerechamcte—zedbyFT瓜，NMR，TEM，SEM，XI乇D，DLSandDSCtechniquesGraRcopolymerizationofEAontoHPMCbackbonewasalsoca幣edoutusing

9、y—radiation(∞Co)bothbythepreirradiationmethodandbythesimunaneousi11radiationmethodintheaqueousmediumThee丘、ectsofradiationenViro啪ent，radiationdose，monomerconcentrationandreaction餾mperatureinte冊sofgraRingparameterswereinVe