雞球蟲病防治藥物篩選與田間推廣應用.pdf

1、Y774727分類號：密級：單位代碼：i0019學號：26047飛嚼差專夭等’碩士學位論文雞球蟲病防治藥物篩選與田間推廣應用ScreeningoftheAnticoccidialEffectsofDrugagainstCoccidiosisandExtendinginField研究指導教生：圭基暨合作指導教師：寶量蟲救援專業(yè)領域名稱：壅陵羞醫(yī)堂型石)f所究方在學2005年1月AbstractChickeoceidiosisisimpor

2、tamdiseasesthathazardousagainstlⅪukryindustryuptodateinourcounUyCoccidiaeasyproducedragresistancethatresultintreatmentandcon仃olfailureTestingEfficiencyofanticoccidialdrugandscreeningnewanticoccidialdrugorpreparationatreg

3、ularintervalswouldbebestmeasureforcontrolchickcoccidiosisDrugefficiencyexperimentandadministeringinfieldwerecompletedforlongtimeuseandmonitoringproductionofdrugresistancebecausedicluzurilwasanexcellentanticoccidiaIdrugTh

4、eresultssatisfiedTheefficiencyofClinacox(Dicluzuril)，MaduramicinandAmproliumwerecompared，theresultasfollow：theACIvalueofMaduramicinexceed180belongtothemostefficiencyanticoccidialdrugtheACIvalueofAmproliumwas135，belongtol

5、owefficiencydrugClinacoxAmproliumandToltrazurilwereofmarkedtreatmentefficiencyagainstdovecoccidiosisUsingdrinkingpreparationofDicluzurilforpreventchickcoccidiosisin05mg／kglmg／kg2mg／kgallthreedosagewereofexcellentefficien

6、cyThepremixpreparationsofClinacox(Diculuzril)，Dicluzuril(madeinChina)，nicarbazinEthopabatewereofmarkedefficiencyagainstcoccidiosis(ACIvalueexceedl80)Nintysixcockerelsweredividedintoeightgroupsin8birdseachat10daysoldAllch

7、ickenofsixgroupwereinnoculatedwithIxl03sporolutedoocystofEtenellaandtreatedwithdiclazurilatI10。atoh，48h，72h，96h，120h，154hpostinoculationrespectivelyTheresultsdemonstratedthatClinacox(contain05％dicluzuril)hadhighefficacya

8、saanticoccidaldruginpreventionandtreatmentofcoccidiosisDiclazurilcouldactonbothsexualandasexualstagesinendogenousstagesofEimeritenellaTheshuttleprogramwasdesignedaccordingtotheresultsasabove：125ppmAmproliumHydrochlorideo

9、r125ppmNicarbazin8ppmEtbopabatemixedin白羽duringl0～30daysold；IppmDicluzurilmixedinfeedduring3t。60daysold；5ppmMaduramicinAmmoniumor60—70ppmSalinomycinmixedinfeedduring61～80ppmThisprogramwasappliedforSijkyfowlandfloorfeeding

10、chickbutonlyusedlaterstagesinbroilerchickTheresultsoffieldtrialshownthatcoccidiosiswascontroledthoroughlyaf【erthisprogramusedinfieldThecoccidiainfectiosityremarkablelight，thebiggestOPGwas1801000incontrolgroup(90daysold)，

11、bmthebiggestwasonly21700inIreatmentgroup，theOPGnearlydifference9timesbetweentwokindsofgroups，fewoocystswasdetectedinyoungerchickgroupChemicalsynthesisartemisinewaspoorefficiencyagainstchickencoccidiosis，didnotsuittoapply

12、forpreventionofcecalcoccidiosisinfieldBasedon96healthymatechickensthisexperimentwasconductedtocompareanticoccidialeffectinQinQiuqingofthreedifferentpercentageandShaqiulingoftwopercentageandselectthehighefficacydrugThechi

13、ckenswererandomlydividedinto8groupsof12eachThisexperimentcontainedsixmedicated，oneinfectedbutnon—medicatedandonenoninfectedandnonmedicatedExceptfortheeighthgroupeachchickenwasinfectedwith70thousandEimeriatenellaisolates，

14、Drugeffectwasevaluatedaccordingtoanticoccidialindex似e1)TheresultshowedACIofeachgroupwas122、132、132、144、182、143、129、200respectivelysoonlythefifthanticoccodialdrugwasofhi曲efficacyTheefficiencyofanticoccidialcompoundswerest