菖蒲、遠(yuǎn)志提取液對老年性癡呆模型小鼠腦組織NO活性、蛋白質(zhì)含量的影響.pdf

1、學(xué)院代號專業(yè)代碼學(xué)號!!!!!!!!密級——陜西中醫(yī)學(xué)院ShaanxiUniversityofChineseMedicine碩士學(xué)位論文菖蒲、遠(yuǎn)志提取液對老年性癡呆模型小鼠腦組織N0‘活性、蛋白質(zhì)含量的影響學(xué)位申請人專業(yè)名稱申請學(xué)位類型指導(dǎo)教師姓名協(xié)助指導(dǎo)教師張偉方劑學(xué)醫(yī)學(xué)碩士科學(xué)學(xué)位王景洪教授頓寶生教授周永學(xué)教授論文提交日期2005年4月TheeffectofChangpu，YuanzhitiquyeaboutNOandprotein

2、inthebrainontheADmodelmiceAbstractobjectiveToinvestigatetheeffectsandthemechanismofChangpu，YuanzhiMethodsResuitsConclusionKeywordstiquyeinJiajiandushuwan(JJDSW)OnthefunctionoflearningandmemorydecreasingofADandtoprovideth

3、eoreticalbasisforclinicalapplicationandexploitingnewdrugsStep—downtestwereusedtoevaluatetheeffectsofChangpu，YuanzhitiquyeonthedisturbanceoftheAlzheimer’SdiseasemodelmicebyScopolaminehydrobromideSimultaneously，thecontento

4、fnitricoxideandcerebralproteinactivitywereobservedasexperimentalcriteriaAllthedatesweredealtwithttestinstatisticsandthePO05wasconsideredbeingdistinctdifferenceChangpu，Yuanzhitiquyecallobviouslyreducethetimesoferrorstep—d

5、owntestandprolongthelatentperiodFurthermore，Changpu，Yuanzhitiquyecanincreasetheactivityofcerebralproteinanddecreasethecontentofnitric—oxideTheresultsshowthatChangpu，YuanzhitiquyeCanremarkablyimprovetheabilityoflearningan

6、dmemoryinADmodelmicethroughincreasetheactivityofcerebralprotein，cleaningnitric—oxidepoisonsandprotectingnervouscellsMeanwhile，ithasdose—effectrelationshipamonglowmiddleandhighdosageAlzheimer’SdiseaseChangpu，Yuanzhitiquye