核因子抑制劑對眼表堿燒傷后白內(nèi)障形成的影響.pdf

1、蘭州大學(xué)碩士學(xué)位論文核因子抑制劑對眼表堿燒傷后白內(nèi)障形成的影響姓名：李之喆申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：魯建華張文芳20090501蘭州大學(xué)碩士學(xué)位論文Influenceofinhibitorofnuclearfactor—KbincataractformationafteralkaliburnAbstractObjectiVe：ThedifferentexpressionofnuclearfactorKappaBinratl

2、ensepithelialcellswasinvestigatedafteralkaliburnintherateyesurfacebetweenexperimentalgroupandcontralgroupInhibitorofnuclearfactorwasusedinexperimentalgroupandnormalsodiumwasusedincontrolgroupMethods：Ocularsurfacealkalibu

3、rnmodelwasmadeinratInhibitorofnuclearfactor(PDTC)O1ml(2IⅡg／m1)wasusedinexperimentalgroupandnormalsodium01mlwasusedincontrolgroupbysub—conjunctiValinjectioneverydayTheratswerekilledinthefirst、third、fifth、seventhdayafteral

4、kaliburnTheexpressionofNF—KBin1ensepithelialcellswasexaminedbyusingimmunohistochemicaltechniqueandreVersetranscription—polymerasechainreactionR蛔u(yù)lts：ThelevelofnuclearfactorKappaBinlensepithelialcellsfollowingalkaliburnwa

5、ssignificantlyhigherincontr01groupthanexperimentalgroupwithinthreedays，whi1etheexpressioninexperimentalgroupwasinhibitedConclusions：EarlyinhibitorofnuclearfactorusingplayansuppressiVer01eincataractformationafterocularsur