腦血流自動調(diào)節(jié)能力評估的研究.pdf

1、蘭州大學(xué)碩士學(xué)位論文腦血流自動調(diào)節(jié)能力評估的研究姓名：申英霞申請學(xué)位級別：碩士專業(yè)：電路與系統(tǒng)指導(dǎo)教師：王煒20090601StudyonevaluationforautoregulationabilityofcerebralbloodflowAbstractCerebralautoregulationisdefinedasamechanismthatmaintainscerebralbloodflowatarelativelycons

2、tantleveldespitechangesofcerebralarteralbloodpressureoverawiderangeImpairedautoregulation，whichmayleadtoischemiaandhyperaemiainthebrain，isassociatedwithpathophysiologicalconditionsincludingintracranialtumours，headinjurys

3、troke，hypertensioninthebrainTherefore，assessingandmonitoringcerebralautoregulationisimportanttoguidethetreatmentsofpatientssufferingfromsuchconditionsAlthoughgreateffortshavebeenmadetodevelopmethodsforassessingtheautoreg

4、ulationusingmathematicalmodelsandsignalprocessingtechniques，theassessmentofautoregulationstillsuffersfromlargevariabilitywhichisnotyetfullyunderstoodInaddition，thereiscurrentlynoacceptedstandardforassessingcerebralautore

5、gulationforclinicalapplicationsInthisthesis，methodsforassessingcerebralautoregulationareinvestigatedandevaluatedusinglinearmodellingapproaches，showingthatthephasedifferencebetweencerebralbloodflowvelocityandbloodpressure

6、isareliableindicatoroftheautoregulationBytheuseofrealtime，fasttimevaryingsystemidentificationmethodstoresearchontrackingbrain’Sautoregulationfunctionofbloodflowwhichcanprovidequantitativebasisforthetreatmentofcerebralvas

7、culardiseaseAtthesametime，theCross—approximateentropyofnonlineardynamicsisusedtostudyautoregulationabilityofcerebralbloodflowinthisthesisTheexperimentalresultsrevealedthatthemethodcanachievereal—time，continuousquantitati