酒渣鼻患者面部微生物寄生狀況研究及細(xì)菌藥敏實(shí)驗(yàn)分析.pdf

1、青島大學(xué)碩士學(xué)位論文酒渣鼻患者面部微生物寄生狀況研究及細(xì)菌藥敏實(shí)驗(yàn)分析姓名：劉俊杰申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：皮膚病與性病學(xué)指導(dǎo)教師：臧運(yùn)書20080607ClinicalSignificanceofthepredominantbacterialstrainsanddemodexonrosaceaAbstractobjective：Tounderstandtherelationshipbetweendemodexandbacteriainf

2、ectioninrosacea；investgatebacteriaflorainthelesionsofthepatientswitllrosaceaandantibioticresistanceofbacteriafrompatientswithrosaceaMethods：Theskinsamplesfromthelesionandtheneighboringregionsin60rosaceapatientswerecollec

3、tedforassay111eskinsamplesWasusedtodetectdemodexonthenasalpartandfrontalregionsebumandtissueonfaceWasscrapedandculturedtoexaminebacteria111ecomparativestudyWasalsomadebymatchingthe60skinsamplesfromnormalcontrols111edataw

4、ereanalysedbystatisticsResults：Rwasfoundthat48(80％)of60Cases、Ⅳimrosaceawereinfectedbydemodex，thepositiveratewashigherwhencomparedwiththenormalcontrolsTheisolationrateofbacteriainrosaceagroupWashigherthanthatnormalthemost

5、commonbacteriaisolatedwasGrampositivebacteria，includingstaphylococcusEpidermidisSsarophyticusandSAureusthemostcommonanaerobeisolatedWaspropionibacteriumGenerallytheywereinthestateofthesubclinicalinefetion111eclinicalinef

6、etionusuallyhappenedwhenthehumanbodyresistanceforbaeteriaWasdecreasedthehumanbodyresistanceforbaeteriamaydecreasedwhendemodexinfectionwasfoundinrosaceaInallofthebacterium，theresistantratetoxithromycinandMetronidazoleWas3

7、92％and996％TheratetoChloromycetinWasthelowest(289％)Conclusion：DemodexandbacteriainfectioninrosaceaareimportantfacorinducingrosaceaThebacterianotoftendetectedinthefacewerenotalsodiscoveredandapositivecorrelationwasnotobser

8、vedbetweenthedemodexandbacteriainfection(PO05)ThemostsensitiveantibioticsforthebacteriaofrosaceaiSChloromycetinPostgraduate：JunjieLiu(Dermatology)DirectedbyprofYunshuZangKeyWords：Rosacea，Demodex，Bacterialculture，Antimicr