茄屬糖苷生物堿在抗真菌活性上的相互作用.pdf

1、學(xué)授代碼：lQi螋分襲號(hào)：盟⑧研究生學(xué)母；密級(jí)；玉東牡嶧蘊(yùn)，|遼碩士學(xué)位論文茄屬捌—爭(zhēng)生物堿在抗真苗活性上的相互tp用Interactionsbetweenthesnianumglycoa|kaloidsjnrelationtoinhibitionoffungulgrowth作肴張強(qiáng)i；戮!i：器。。。；；謄冀：；籌東北師范大學(xué)學(xué)位譚定委員會(huì)2007年6月AbstractGlycoalkaloidsaresecondarymetabol

2、ismofplantsanddistributedmainlyinSolanaceaeandLiliaceaeThesemoleculeshavealloligosaccharidechainattachedattheC3positionofthem仃ogenoussteroidalalkaloidbackbonethesugarchainareuauallytrisaccharideortetrasaccharideSomeinves

3、tigationhaveindicatedthatglycoalkaloidsmasthavebeenevolvedinnaturetoprotectplantsagainstbacteriafungi，insects，andanimalsTheyaretoxictoawiderangeoforganismsandaregenerallyconsideredtobedefensiveaUelochmicalsThebiologicala

4、ctivityofglycoalkaloidsislargelyduetotheirmembranedisruptiveeffectsTheycomplexwithsterolsinmembranes，ultimatelytoformaggregatesandcauselossofmembraneintegrity‘Thestudyabouttheuntifungalactivityofglycoalkaloidsisanimporta

5、ntmoietyintheecologyandexploitationofplantresourcesButmuchlessinformationisavailableonthesecompoundsinchinaInadditioninmanysolanaceonsspecies，themajorglycoalkaloidspresentarepairsofstructurallyrelatedcompoundswhichsharea

6、commonaglyeoneanddifferonlyintheircarboh)7&atemoietyInterestingly，Someofthesenaturally‘paired’glycoalkaloidssharethecarbohydratemoietiesofSolanine(solatriose)andchaconine(chacotriose)differingonlyinaglyconestructureegsol

7、amargineandsolasonineWithregardtomembranedisruptiveactivity，chacotriose—basedglycoalkaloidsarenormallyhighlyactivewhereassolatriosebasedcompoundsshowlowerornoactivityThereisevidencetoothatsuch‘“paired’glycoalkaloidsmayin

8、teractsynergisticallySoitisvaluableforUStounderstandandstudythebiologicalactivityofglycoalkaloidstheirmixturestopathogenicfungiinchinaInthispaper、析mtwophytopathogenicfungiCercosporellabrassicaeHoelmelandAlter詫ariaporriCi

9、fastextedstrainthecharacteristicsofantiftmgalactivityofsolamargine，solasonine，chaconine，solanineandtheirmixtmeWareexaminedbymeallsofinhibitionofmycelialgrowth111emainresultsobtainedfiomthisworkareasfollows：1Theglycoalkal

10、oidsshowapronouncedconcentrationdependencyintheirinhibitionofpathgenicfungalgrowthChaconinewasthemostinhibitoryandsolaninewastheleastinhibitoryofthefourcompounds2Themixturesofsolamargineandchaeonine／Solasonineandsolanine

11、producedadditiveeffectsanddidn’tproducesynergisticeffectsonantifungalactivitytheinhibitioncausedbytheglycoalkaloidmixturewereequivalentwiththeexpectedvalues(based011summingtheindividualactivities)Keywords：Glycoalkaloids；