Wittig反應(yīng)及其在維生素A和類胡蘿卜素合成中的應(yīng)用.pdf

1、浙江大學(xué)碩士學(xué)位論文Wittig反應(yīng)及其在維生素A和類胡蘿卜素合成中的應(yīng)用姓名：澹臺(tái)峻申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：化學(xué)指導(dǎo)教師：李浩然20040201浙江大學(xué)理學(xué)碩士學(xué)位論文AbstractThisdissertationreviewtheapplicationofWittigreactioninorganicsynthesisandsynthesisofvitaminA，astaxanthinandcanthaxanthinWedescr

2、ibedsomeimportantpartsofWittigreactionylide，alkaliandmedium；stereochemistryofstabilizedylide，semi—stabilizedylideandnon—stabilizedylide，respectivelyThemaincharacterofWittigreactionisthatthepositionofCCdoublebondiscomplet

3、elydeterminatedAndthereactiontakeplacewasinconditionofbase，roomtemperatureorlittlehigher(10wtemperatureatsomecondition)Sothisreactionisfittedforthesynthesisofolefincompound，suchasvitamins，carotenoidsThisdissertationstudy

4、thesynthesisofVitaminAacetateusedinWittigReaction，withfewstepsofreaction，higherpureproductionandlowcostSoweprovidethereliabledatefortheimprovedprocessofvitaminAacetateinChina；Continuousprocesstosynthesisandisomerizationo

5、fvitaminAacetateCanget90％orhighall—transproduct，whichishigherthanliterature；WehaveestablishedthedynamicalmodelofsynthesisofvitaminAactetateforthefirsttimeTheisomerizationreactionshavebeenstudiedusingquantumchemistrymetho