原發(fā)性乳腺血管肉瘤的個案報道及文獻研究.pdf

1、浙江大學醫(yī)學院碩士學位論文原發(fā)性乳腺血管肉瘤的個案報道及文獻研究姓名：周晟昂申請學位級別：碩士專業(yè)：臨床醫(yī)學指導教師：丁克峰20090401浙江大學碩士學位論文英文摘要PrimaryAngiosarcomaoftheBilateralBreast：ARareCaseReportandLiteratureReviewAbstractPrimaryangiosarcomaofthebreast(PAB)isararetypeofmammar

2、ymaligantsarcomaabout005％ofallthemalignanttumourofbreastTheformofPABoccuredinbilateralbreastisevenmoreinfrequantlySincelittleisknownaboutthebiologyofthisraretumouritisusefulteporteverysuchcase，inordertomakeaSmuchinformat

3、ionaspossibleavailableinthemedicalliteratureWepresentthecaseofa39yearoldChinesewomanwithaPABtreatedbymastectomyofrightbreastin2005，thenanothertUl[nOrwasfoundinthecontralatbreastandtreatedbymastectomyin2008Thediagnosisofa

4、ngiosarcomaofthebreastWasconfirmedChemotherapyWasnotprescribedTherarityandthepoorprognosisofthisdiseasecausedUSgreatinterest，especiallyoriginatedinbilateralbreastTheauthorsreviewtheliteratureandsummarizerelevantfindingsc

5、oncerningdefinitionpathologyclinicalpicture，treatmentandfollowupPositiveratioofendothelialcellmakers(AntiFVlIIILCD31，CD34，UEA1，eta1)andVEGFisrelativelyhighBesidesfineneedleaspirationandbiopsyUltrasoundXrayandMRImayhelpto

6、diagnosisWethinkthatthesurvivalratedependsontumorsizeandtumordifferentiationSurgicalresectionfollowedbychemotherapymaybeprovedtobeeffectiveinfutureandaffordthebestprognosisTheeffectofchemotherapyradiotherapyandtargetedth