MRI靜磁場對心電圖T波影響機制的仿真研究.pdf

1、浙江大學碩士學位論文MRI靜磁場對心電圖T波影響機制的仿真研究姓名：羅如意申請學位級別：碩士專業(yè)：生物醫(yī)學工程指導教師：夏靈20060601③浙江大學碩士畢業(yè)論文AbstractElectrophysjolo舀cal鋤dcellularlevelstlldyofh啪壯c刪v嬲cularsystemillfluencedbySMF(StaticMa印eticField)isofgreatimponanccnisnotonlyhelpful

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3、VemetIlodssuchascomputersimulationscangainsomeusefIlliIlfomationonthebasisofprevioussimulationstudies，wecombinemagneto_hydmdynamicsmodelwitllelectrophysiolo百calheartmoddtostudythemech壯ismofECG—TwavechangeinSMFktlIisthesi

4、s，based叫ma髓et0hydmdyn鋤icsmodel柚dbych粕百ngtheintensityofSMF，wecalclllatethevolumeflowratcofaonabymeansof血iteelementmethod，alldgetinduccdV01tageandcurreⅡtfigur髂Bascdonionic—chanⅡelmodelofthec盯diacVentricularceU，wesilnulated

5、j仃eremdegrceofalloxiabycbangiⅡgthcpe咖eabjlityofA，rPdependcnceofLtypecaldumchallndIK(冊)sprillgcdbyacute柚oxiaandlca㈣ch蛐gewithfArP】iarcc0璐ideredMe卸w瑚e，ac廿onpotentials(A_P)of印icardial，MceUalldendocardialcellatdifferentiIIten

6、sitvofSMF盯ealsosimulatedultralIi曲SMFcouldiⅡducemoretllall10％rcducti∞oftllevolumenowmteofthebloodjnhumanarota，thuscalIpmduceanoxiaconditi0IlOfacuteischemiaFunhe姍orc，wesimulatetheiIIducedvoltag髂趾dcIl盯entsindi如rcntilltensit

7、y0fSMF11lecardiacactionpoteJnialplateauissupprcssed如dthusshonentheacti∞potentialduration㈣D)，wllichrcsuninenhancedt陽nsmuralheterogeⅡeity11helargestofAPDdecreaseisiIlepicardialcell，andtIlesmallestinendocardialcell_T1leECGT