腹腔鏡宮頸鱗癌手術并卵巢側面移位術后卵巢內分泌功能及并發(fā)癥的研究.pdf

1、石河子大學碩士學位論文腹腔鏡宮頸鱗癌手術并卵巢側面移位術后卵巢內分泌功能及并發(fā)癥的研究姓名：楊萍申請學位級別：碩士專業(yè)：婦產科學指導教師：王英紅20080601ABSTRACTOb—iective：Toinvestigatethefactorsofinfluencingtheovarianfunctionandthesequelaeinyangwomen謝mearlystagecervicalsquamouscarcinomawhoun

2、derwentradicalhysterectomypelviclymphadenectomyandLOT(1ateralovariantransposition)，andtheobjectiveindicatorsofmonitoringtheovarianfunctionMetho。d—s—：22youngercervicalsquamouscancerpatients(surgeryage45years)including19ca

3、seswhounderwentradicalhysterectomypelficlymphadenectomyandLOTand3caseswhoseovarianwereretainedinsituwererecruitedtoourstudyWeusedtheKuppermanstandard(1995)toinvestigatetheclimactericsyndromeofthepatientsandcombined謝餓FSH，

4、LH，E2andInhibinB(INHB)tojudgeovarianfunctionAndwealsousedultrasoundtoimagethetransposedovariestofmdoutthesequelaofLOTResu1ts：——ThefemalehormonelevelsandKuppermanscoreof13caseswhounderwentLOThadnodifferencebeforeoperation

5、andafteroperationinsixmonthsp005)ThelevelofFSH，LH，KuppermanscoreinLOTandpostoperationradiotherapygrouparehigherthanthatinthenadiotherapygroup畔005)，butweresignificantlyhigherthanthatwhoseovarianwcTeretainedinsitu畔0。05)In7

6、patientswhoacceptedthesurgeryin40—45yearsold，2patientshadnormalovarianfunction，5patientswhoseovarianfunctionweredeclinedIn12patientswhoa唧tedthesurgerylessthen40yearsold，9patientshadnormalovarianfunction，3patientswhoseova

7、rianfunctionweredeclined，inallthetwogroupstherewerenotovariandysfunctioncases，therateofnormalovarianfunctionbetweenthesetwogroupswasnosignificant∽005)Inthe19LOTpatients，noonewhosetumourcellWasspread，onlyonecasehadpelvice

8、ffusion，anddisappearedafterhalfofmonthbytherapy，onehadintermittentslightpaillintherightpositionwheretheovarianWagtransposed；。Inthe22cervicalcancerpatientsreceivedoperation，withthedeclineofovarianfunction，thelevelofINHB，E

9、2wasdeclined，andthelevelofFSHWasrosegradually；thedifferentWassignificantbetweenthegroupofnormalovarianfunctionandthatofdeclinedovarianfunction，aswellasthegroupofnormalovarianfunctionandthatofovariandysfunction畔005)Conc。1

10、u。sion—：—LOTiseffectiveinretainingtheovaryfunctionsofearlystagecervicalsquamouscarcinomapatientsPelvicradiotherapyafarLOTcangreatlyprotecttheovaryfunction，butitalsopartlydamagethetransposedovarianThepatientsmorethan40yea

11、rsoldcanalsobenefitfromLOTTherateofsequelaeafterLOTisverylow。JustasFSH，INHBisalsosensitiveindicatorthatreflectsovarianfunction。Keywords：cervicalsquamouscellcarcinoma；ovariantransposition；ovarianendocrinefunction；sequelae