特發(fā)性黃斑裂孔手術前后的VA、mfERG及OCT的變化分析.pdf

1、武漢大學碩士學位論文特發(fā)性黃斑裂孔手術前后的VA、mfERG及OCT的變化分析姓名：俞曉藝申請學位級別：碩士專業(yè)：眼科學指導教師：楊安懷喻長泰20040410AbstractObjective:Toobservethechangesofvisualacuity(VA)、multifocalelectroretinogram(mfERG)andopticalcoherencetomography(OCT)beforeandaftersuc

2、cessfulidiopathicmacularhole(IMH)surgeryevaluatetheeficiencyofvitreotomyandanalyzetherelationshipsofthose.Methods:18eyesof18patientswithsuccessfulvitreotomyforIMHwerecollected.TheywereexaminedbyVAmfERGOCTpreoperativelyan

3、dI、3612monthspostoperatively.Theresultswereanalyzedcomparedto25eyesofcontrolgroup.Result:(1)Postoperatively17eyes(94.44%)hadanatomicclosureofthemacularholeconfirmedbyOCTin1monthandnorecurrencein12months.Just1eye(5.56%)fa

4、iledinclosure.(2)VAofIMHeyesimprovedsignificantlypostoperativelyespeciallyduring6monthsthanpreoperatively(P0.01).(3)BeforeoperationthemfERGtopographiesofIMHeyesseemlikevolcanoesbecausetheresponsedensitiesofwavePofring1an

5、dring2werelowerthancontrolgroupwhiletheotherthreeringskeptinnormal.AftersurgeoncenterpeaksofmfERGtopographiesreappearedlitlebylitleduringIyeartheresponsedensitiesofwavePofring1andring2werehigherthanbefore(P0.05)butstilll

6、owerthancontrolgroup(P0.05).(4)Thethicknessoffovearetinanerveepitheliumlayer(FRNEL)measured勿OCTof17eyeswithanatomicclosurewasnolongervariedandkeptlowerthancontrolgroupthroughoutthefollowuptime(P0.01).(5)Oneyearpostoperat

7、ivelytherewerepositivecorrelationsbetweenVAandmfERGandFRNEL(P0.01).Conclusions:VitreotomyisusefulforIMHwhichcanbeevaluatedbyVAmfERGandOCTcorrectly.Keywords:IdiopathicmacularholeVisualacuity(VA)Multifocalelectroretinogram