阿托伐他汀和尼可地爾治療冠狀動脈慢血流的臨床研究

1、分類號：R541.4密級：UDC：610學(xué)校代碼：11065碩士學(xué)位論文阿托伐他汀和尼可地爾治療冠狀動脈慢血流的臨床研究王明磊王明磊指導(dǎo)教師陳作元教授學(xué)科專業(yè)名稱內(nèi)科學(xué)（心血管病學(xué)）論文答辯日期5015年5月30號萬方數(shù)據(jù)青島大學(xué)碩士學(xué)位論文2AbstractObjective:ToinvestigatetheclinicalefficacyofAtvastatinCombinedwithnicilinthetreatmentpreve

2、ntionofconaryslowflowadversereactionprovidemeexperiencefclinicaltreatment.Methods:romlyedfrom2012Januaryto2014January9intheDepartmentofCardiologyofAffiliatedHospitalofQingdaoUniversityMedicalCollegediagnosedbyconaryangio

3、graphyinpatientswithslowbloodflowwasobservedin60patientsromlydividedinto3groupseachgroupof20peopleweregivendifferenttreatmentonegroupreceivedatvastatintherapyanothergroupwasgivenNicoleE1thelastgroupoftheAtvastatinCombine

4、dwithnicilcombinedtreatment.TheanteridescendingconaryarterycollectingthepatientbefethetreatmentofthecircumflexarteryangiographyrightconaryarterybloodframesmadeinthepatientinfmedconsentfromthevalueofvenousbloodplasmahsCRP

5、ET16minuteswalktestresults.Thesubjectswereprescribedmedicationaccdingtotheexperimentaldesign3monthsoftreatmentthisprocesswasnotfollowedupregularlythepatientsintrialaweektodoaroutineECGexamination3monthsaftertheendnumeric

6、alcheckagaintheplasmalevelsofhsCRPET16minuteswalktestresultsrecdstatistics3withinamonththepatientswithchestpainchesttightnessthenumberofattacksothersymptomsadversereaction.AllthedatawereanalyzedbyusingSpss16.0statistical

7、software.Results:3groupsofpatientsbefetreatmentconditionbasedonthecomparisonofconaryflowimagingframeswerenotstatisticallysignificant(plessthan0.05)3groupsofpatientsaftertreatmentbefetreatmentplasmahsCRPET1avalueof6minute

8、walktestresultswereimproved(plessthan0.05)intheviewofhsCRP:afterthetreatmentofnumericalcombinationgroupthantheAtvastatingroupatvastatingroupBinikediernumericalatvastatingroupislowintheviewofET1:lownumericalcombinationgro

9、upBinikedieraftertreatmentgroupnicilgroupsimvastatingroupvaluelowerthanasupptinthe6minutewalktest:treatmentafterthenumericalBinikediercombinationgroupwerehigherthanthevaluesnicilgroupatvastatingroupwashigh.Incomparisonto

10、thedegreeofimprovementoftheclinicalsymptomscombineddruggroupthanatvastatingroupnicilgroupimprovedsignificantlythedifferencewasstatisticallysignificant(P0.05)nicilgroupthanatvastatingrouptreatmenteffect(plessthan0.05).Adv

11、ersereactionsof3groupshadnosignificantdifference.Conclusion:atvastatinnicilalonecaneffectivelyimprovetheslowflowconditiontheeffectofnicilwasbetterthanatvastatincombinedwithatvastatinnicilinpatientswithoutincreasingadvers

12、ereactionsatthesametimecanbemeeffectiveinthetreatmentofslowflow.Isawthyofclinicalreferencetreatmentmethodinviewofthesmallsampleinthetesttheconclusionhassomelimitationsthistopicresearchexpectedlaterwillhavelargersamplesto