磷?；愣顾氐暮铣珊褪中源呋瘎┑脑O(shè)計(jì)、合成及其在不對(duì)稱催化中的應(yīng)用.pdf

1、西南大學(xué)碩士學(xué)位論文磷?；愣顾氐暮铣珊褪中源呋瘎┑脑O(shè)計(jì)、合成及其在不對(duì)稱催化中的應(yīng)用姓名：王亮申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：分析化學(xué)指導(dǎo)教師：彭云貴20061201弧南大學(xué)化學(xué)化工學(xué)院碩‘宄生畢業(yè)論文Thesynthesisofphosphoryli：oumarinsandthedesign／synthesisofchiralorganocatalystanditsapplicationinasymmetricsynthesisMaster

2、ofAnalyticalChemistry：WangLiangInstructor：ProfessorYunguiPengAbstractAseriesofeollmarilMwefephosphorylatedwitIIdiisopropylphophite(DIPPH)anddiethylphosphitefDEPPH)byAthertonToddreactionin6496％yieldssuccessfullyandthecoum

3、arinderivativeswitlbighpharmaceuticalvaluewe”obtainedbychemicalmodificationAnumberofaldehydesreactwithaceticanhydrideinthepresenceofcatalyticamountofbetazeolitetoaffordthecormpondh_lg1，1diacetatesingoodtoexcellentyieldsT

4、hebetazeolitehasshowedhigllcatalyticactivityinthisructionL()Tartaricacidisusedasstartingmatenaltosynthesizeaserialofchiraltetraphenyldiolswhichcallbeusedasthe]iganasintheasymmetriccatalysisreactionsfls，2s)()t，2Diphenylet

5、hyleneDiamineissynthesizedfrombenzaldehydein6steps，themethodissimpleandreliableandtheyieldisllig虹HomochiralⅣS2s)(十1，2DiphenylethyleneDiaminewasusedasthestartmaterialtosynthesizeaseriesofchira]bifunctionalthioureaswithrea

6、ctiveful烈JongroupsandtrytouscthemtocatalyzetheMichaeladditionof∞c∞dafyaminesuch∞pyrrolidineto2(5n)faranoneChiralbifunetionalthiourea塒thschi行basew∞foundtohavegoodsolubilityandpropercatalyticgroups；itisverypromisingtoasymm

7、etricallycatalyzetheMichaeladditionofsecondaryamineto口B—unsaturatedlactonesViatheresearchingworkofthisdissertation，newnotionhasbeenputforwardtoasymmeuicallycatalyzetheMichaeladditionofo，13一unsaturatedlactonesThisnHIlc％it