胃蛋白酶原及其亞群與CA72-4聯(lián)合檢測對早期胃癌診斷及預(yù)后判斷的意義.pdf

1、青島大學(xué)碩士學(xué)位論文胃蛋白酶原及其亞群與CA724聯(lián)合檢測對早期胃癌診斷及預(yù)后判斷的意義姓名：林惠忠申請學(xué)位級別：碩士專業(yè)：普通外科指導(dǎo)教師：周巖冰20050524TheDiagnosticandPrognosticSignificanceofPepsinogenwithIt’SSubgroupandCA724onEarlyGastricCancerAbstractlobjeetivelTodiscusstheinfluenceofse

2、rumpepsinogenanditssubgroups(PGI、PGII)withCA724onearlydiagnostisandpostoperativercculTellceandtoevaluatetheeffectsondiagnosisandprognosisingastriccancerpatients【Methods】RadioimmunoassaywasappliedtodetectthelevelsofserumP

3、GI、PGIIandCA72—4ongastriccancerandotherstomachdisease，comparedthosewiththenormalcontrolgroupTheresultwereanalyzedbystatisticsmethodIResults】Comparinghealthycontrolswithgastriccancer(GC)anditsdifferentstagescases，theserum

4、PGlevelsofGCpatientsweresignificantlylowerthanthoseofcontrolgroups(pO01)，theearlygastriccancerhadshowedapparentchanges(p005)，andadvancedGCwereevenlower(p001)CA724concertrationinearlystagegastriccancerhadnodifferentcetoth

5、ehealthyoneapparentlyOtherwiseThoseWerehigherlysignificantlyinadvancedGCTheserumPGI、PGIIandCA724levelswerechangeddifferentlyafertheoperation(p0oi)ThesenlmlevelofPGdecreasedgrosslyinthepatientsunderwentradicaltotalgastrec

6、tomy，butPGI，PGIIandCA724wereelevatedremarkablyintherecurrentpatientsBesidesCA72—4，theserumlevelsofPGI，PGIIhadnotaltereddmmaticlyintherelapsedradicalsubtotalgastreetomypatients，Thosecombinatedprocesuresshowedmuchmorespeci

7、ficitytoapply1Conclusion】DetectingtheserumlevelsofpGI，PGI／IIshouldbeusedtoscreen，earlygastriccancerIftcombinetheCA72—4detection，thesemethodsshouldbemodifiedmoresensitivelyandspecificly，andappliedtoobservemaysignificantly