低功率半導(dǎo)體激光照射對多孔羥基磷灰石義眼臺血管化影響的實驗研究.pdf

1、南昌大學(xué)醫(yī)學(xué)院碩士學(xué)位論文低功率半導(dǎo)體激光照射對多孔羥基磷灰石義眼臺血管化影響的實驗研究姓名：肖衛(wèi)申請學(xué)位級別：碩士專業(yè)：眼科學(xué)指導(dǎo)教師：廖洪斐20090601AbstractABSTRACTobjective：Toinvestigatetheeffectsoflowenergysemiconductorlaserirradiationonvascularingrowthintorabbitscorallineporoushydroxy

2、apatite(CHA)orbitalimplantsMethods：ThirtyNewZealandwhiterabbitswererandomlydividedinto3groups(groupA、B、C)，eachofwhichhas10rabbitsTherabbitsofgroupAtaken舔controlgroupunderwentrighteyeenucleationwithplacementofCHAimplantsT

3、herabbitsofgroupBunderwentrighteyeenucleationwithplacementofCHAimplantscombinedwithlowpowersemiconductorlaserirradiationonsurgery“eye(eachrabbitWascontinuouslyirradiatedfor5daysinthreedaysafteroperation，onceeverydayfivem

4、inutes)TherabbitsofgroupCunderwentrighteyeenucleationwithplacementofCHAimplantscombinedwithlowpowersemiconductorlaserirradiationonsurgery“eye(eachrabbitWascontinuouslyirradiatedfor5daysinthreedaysafteroperation，onceevery

5、dayfiveminuteseachrabbitWascontinuouslyirradiatedfor5daysafteroneweek)TherabbitswereclinicallyexaminedforinflammationandimplantsexposureeverydayafterimplantationAt1、2、4、6and8weekspostoperatively，theaverageradioactivecoun

6、tsofbothorbitsinthesameanimalweremeasuredandtheR|Lratioswerecalculated。At8weeeksimplantswereextractedandexaminedhistopathologicallytocomparethedifferenceofthethreegroupsinthedegreeoffibrovascularizationoftheimplantsResul

7、t：12。4weeksafteroperationtheaverageR|LratiosoftheCHAorbitalimplantsaddedupweeklygroupAwaslowerthangroupB，C(P005)whilethedifferenceoftheR|LratiosbetweengroupB。CWash’tsignificant68weeksafteroperation。theaverageR|Lratiosamo

8、ngthreegroupshadnosignificantdifference燦1theCHAorbitalimplantshadfibrovascularizationat8協(xié)weekConclusion：1)LowpowersemiconductorlaserirradiationonsurgeryeyecouldpromotethefibrovascularingrowthintoCHAorbitalimplantsinearly