卵巢顆粒細胞瘤中Bcl-2、Bax和Ki-67的表達及其意義的研究.pdf

1、山西醫(yī)科大學(xué)碩士學(xué)位論文卵巢顆粒細胞瘤中Bcl2、Bax和Ki67的表達及其意義的研究姓名：梁曉艷申請學(xué)位級別：碩士專業(yè)：病理學(xué)與病理生理學(xué)指導(dǎo)教師：姚漢武路喜安20100315山西醫(yī)科大學(xué)碩士學(xué)位論文ExpressionofBc卜2、BaxandKi67i11ovariangranulosecelltumoura11dthesignificanceAbstractObjectiVe：T0detecttheeXprcssionofBcl

2、2、Bax鋤dKi67i11ov撕an鯽1ulosacelltIlmo吐AndtoexploretheeXpressionofBcl一2alldBaxiIl也edevelopmentofovari鋤伊刪losacelltLllnoura11dtllerelationshipb嘶veenthemT0eXploretheroleofBcl一2鋤dBaXiIlmedeVelopmentofoVadaIlgBa芏lulosacelltumo峙a

3、lldtostudymerelationshipbetwe：entheexpressionofmemandthebionomicsofoVariang啪ulosacelltumourBesides，wet巧t0stlJdytIlerelationsllipbe“忙enⅡleexpressionofthemandtumourstlistolo西calcl硒sification，clillicalstage觚dtlistologicalgr

4、oupingW|e仃ytoexploretlleValueofthemiIlp托dictingnlepro印osisofoVari鋤GCTMethOdS：43casesoftheovari鋤gr鋤ulosacelltumourand24c嬲esofnonnalovaryweredetI獻ed0nTissueMicroa而es，tlleexpressionofBcl2、BaX鋤d飚67w勰Ineasured誦mh姍岫ohistCheIIl

5、i晦nere剛tswere觚alyzed、)IritllSPSS115statisticalso‰礎(chǔ)Results：①Inm毒nonIlalova以everyilldexoIllyexpressiIl筍anulosacellsofpriI：naDrfoIlicles觚dSecondaryfollicles，butllas110expressioniIlthepdmtiveandmaturefollicles1he嘶osofhypoeXp

6、ressionofBcl2，Ba】【鋤d飚一67be鉚eenthe研maDrfollicles觚d也eseco咖follicleshaSn0si嘶jEic觚tdi虢renee(P005)②TheexpressionofBcl2孤ld鬟j一67bc懈eentheno肌aJova巧鋤dtlleoV撕aIl鏟咖lo阻cellturnollrhaSsigllificantdi旅黯nce(P005)③TheexpressionofBcl2inIl

7、istologicalgroupingl娜sigllificantdi位rence(P005)⑤，nleeXp螨sionof硒一67hassi鰣ficantdi虢rence(P005)t哪。時sdi虢rentiation，cliIlicalstage鋤dllistologicalgroupingofoV撕an伊鋤ulosacellttlmourCOncIusionS：①DetectionofnleexpressionofBcl2、Bax

8、and飚167candetenlline吐lebiolo西calbehaviorofoVari鋤GCT觚dhelpllst0know恤deVelopmentof也en珊。啦②Tkexpression0fBcl一2aIld硒67isconcemed婀tllnledevelopment0fov撕allGCT③llistologicalgroupingcanbeused私areferredfactort0eValuate廿leprognosi