誘導(dǎo)型一氧化氮合酶在不同年齡組皮膚自然衰老中的表達及意義.pdf

1、中南大學(xué)碩士學(xué)位論文誘導(dǎo)型一氧化氮合酶在不同年齡組皮膚自然衰老中的表達及意義姓名：王琦申請學(xué)位級別：碩士專業(yè)：皮膚與性病學(xué)指導(dǎo)教師：謝紅付20070501中南大學(xué)碩士學(xué)位論文英文摘要AbstractObjective：ToinvestigatetheexpressionOfiNOSinunexposedskinfmmdifferentagegroups，andstudythemleofiNOSintheprocessofskinintr

2、insicagingMethods：30unexposedskintissuefiomdermatoplasticoperationpatientsofdifferentagewerecollectedanddividedintotwogroups：theteenagegroupunder20yearoldandtheoldagegroupbeyond40yearoldTheexpressionofiNOSofeachcasewasde

3、tectedbyRTPCRandimmunohistochcmistryandthedifferenceofeachgroupWCTCanalyzedResults：1TheproteinofiNOSwaslocatedinkeratinocytes0fepidermis，paficularlyinstratumbasaleTheexpressionlevelofiNOSinteenagegroupwaslowandmodcratean

4、dthelevelofoldagegroupⅥ懈moderateandhiglLSothelevelofiNOSinoldagegroupwassignificantlyhigherthaninthetillagegroup∞001)；2theexpressionlevelsofiNOSmRNAintwogroupsWb豇eO3552士0065307475：￡00767respectivelyThelevelofiNOSmRNAinol

5、dagegroupwassignificantlyhigherthanintheteenagegroup∞o01)Conelusion：TheexpressionlevelofiNOSwasincreasedwithageThefmdingssuggestexithatiNOSmayplayapositiveroleintheprocessofskinintrinsicagingKEYWORDS：iNOS，intrinsicagingo