中樞的惡性神經(jīng)鞘膜腫瘤—17例臨床研究報(bào)告.pdf

1、復(fù)旦大學(xué)碩士學(xué)位論文中樞的惡性神經(jīng)鞘膜腫瘤—17例臨床研究報(bào)告姓名：謝清申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：外科學(xué)指導(dǎo)教師：鮑偉民20030520復(fù)日大學(xué)碩十研究生畢業(yè)論文AbstractClinicalanalysison17casesofcentralmalignantnervesheathtumorsPurpose：‘rhroughanalyzingclinica]data()f‘a(chǎn)groupel’cenLralmalignantnerves

2、teathtumors(CMNST)，includingtumorswhichorigihatefromcranialnerveroot，spinalnerverootornearbycentralnervoussystem，wemayunderstandmoreaboutthiskindofFare1umorMethodandMaterials：FromJan1994to0ct2002，24CMNSTswerediagnosedand

3、treatedatourdepartment，HuashanhospJtal，17ofwhichhavebeenful1ydocumentedHereweretrospectivelYanalyzethem，whicharecategorizedintothreesubgroupsbytheirorigins，oneisfromcranialnerveFOOL，anotherisfromspinalnerveroot，theotheri

4、sfromunspecifiedcentralnerverootResult：Thereare11maleand6femalepatientsranginginagefrom3to65years(meanage，311)，onlY2ofwhichhavefibromatosishistoryThediseaseprogressingofCMNSTisfrom1monthto4years，10ofwhichshowedupsymptoms

5、in3monthsComputerizedtomography(CT)andmagneticresonanceimaging(MRI)revealstUmOFSmainlYinvasivegrowingwithhomogeneousenhancementHistologicallY，thetumorrellsiflthepredominant]Yhighrellularregionaremadeupofspindleshapednucl

6、eiandarrangedinstoriformpatterns，somewithcyst，hemorrhage，calcificatiOil，ornecrosisP1eomorphismandnumerousmitoticfiguresarenoted，buttypicalAntoniA／BstructuresarerareImmunohistoehemicallY。thetumorCellSaremostlYpositiveforS

7、100andVimentinproteJn7caseshadtumorstetalremoval，7casessubtotalremoval，and3partialremovalMostofthepatientsrecoveredquicklyafteroperations，andthe5yearSUFVivalratesareonlY235％though4patientsofthemhavesurvivedmorethan6years

8、Conclusion：TheCMNSTsaFemorecommoniYseeninchiIdrenortheelderwithnerverootoriginOFunspecifledoriginnearby，accordinglYshowingsymptomsandsignsorientedtotheregionoftumorsThec1inicaImanifestationofCMNSTisn’trathertypicalManage