A型肉毒毒素治療痙攣型腦性癱瘓跖屈畸形的療效分析.pdf

1、遵義醫(yī)學院碩士學位論文A型肉毒毒素治療痙攣型腦性癱瘓跖屈畸形的療效分析姓名：李同歡申請學位級別：碩士專業(yè)：兒科學指導教師：束曉梅201205遵義醫(yī)學院碩士學位論文A型肉毒毒素治療痙攣型腦性癱瘓跖屈畸形的療效分析EffectsofBotuHnumatoxinIn]ectiononTiptoeDeformationwithSpasticCerebralPalsyAbstractob]ective：Toinvestigatethetherap

2、euticeffectofbotulinumAtoxin(BTXA)injectionontiptoedeformationwimspasticcerebralpalsy(scP)，andthenewtreatmenttotiptoedeformationMethods：62SCPchildrenwimtiptoedeformationinourstudyfromJune2010toNov2011，weredividedinto4gro

3、upsbasedonthelevelofcalftricepsmusculartensionandankledorsiflexionangle，groupI(20cases)，musculartensionIandIlevel，ankledorsiflexionanglefrom00to一150；groupII(19cases)，musculartensionlevelII，ankledorsiflexionanglefrom00to一

4、150；groupIII(15cases)，musculartensionlevelIII，ankledorsiflexionanglefrom250to350；andgroupIV(8cases)，musculartensionlevelIvankledorsiflexionanglefrom350to45062childrenweretreatedbyBTXAblockThegastrocnemiusandsoleusmuscles

5、werelocatedbyperipheralnervestimulatorsurfacemodeandinvivomodelAfterinjectedw油BTX—Athirddayfirstweek，firstmonth，nlirdmonthandsixthmonthtoinvestigatethetherapeuticeffectbymeasurementofankledorsiflexionangleandevaluationof

6、calftricepstensionvariationResults：Bothankledorsiflexionangleandcalftricepstensionvariationweresignificantdifference1stmonthand3rdmonthaftertheinjectionofbotulinumAtoxininineachgroup(PO05)Calftricepstensionwerelowerandth

7、eankledorsiflexionangleweregreaterbeforeinjectedwimBTXA，theeffectwillbetterNonecasesWimallergicreaction，only1patienthadtemporarymuscleweaknessandbeganrealivingat1weekafterinjectionConclusion：1InjectingBTX—Aisaneffectivem