乙酰肝素酶與妊娠期高血壓胎盤淺表植入相關(guān)性實驗研究.pdf

1、內(nèi)蒙古醫(yī)學院碩士學位論文乙酰肝素酶與妊娠期高血壓胎盤淺表植入相關(guān)性實驗研究姓名：張文娟申請學位級別：碩士專業(yè)：人體解剖與組織胚胎學指導(dǎo)教師：任明姬201005010ThecorrelationStudyaboutHeparanaseandSuperficiMplacentalimplantationinSuperficialimplantationAbstractObjectiveThenormalbloodpressure，mater

2、nalandseverepregnancy—inducedhypertensioninthematernalplacentaheparanaseexpressionandtheplacentaltissuemicrovesseldensitywerestudiedTheembryoimplantationfactorsOiltheheparanasewereexploredMethods30causesofseverPIHwasasth

3、etestgroupand30causesofnormaltissuewasasthecontrolgroupThepositiveheparanaseexpressionwasobservedbyRT—PCRmethodTheHpaandCD34werestudiedbyimmunohistochemicalmethodUnderthehighpowerfield，thecellsweredividedbythesectionssta

4、inedcellscytoplasmandmembraneAnd，inhighpowerfield，fivethenumberofcapillarieswithinthefieldofvisionWascountedtoseektepresentthemeanMVDThedataWasanalyzedbySPSSl30statisticalanalysissoftwarepackageasP=005ino耐ertoteststandar

5、dResultsThehep扣anaseWasexpressedinthenormalpreg—nancygroupandthegestationalhypertensiongroupInthenormalpregnancyplacentaltissue，theaverageopticaldensityofheparanaseWas02590003178and01710005043inpregnancy—inducedhypertens

6、ionThetwoaverageopticaldensityweredifferentesignificantly(PO05)Inthenormalpregnancyplacentaltissue，MVDWas67911690and57514154inpregnancy—inducedhypertensionMVDintheexperimentalgroupwaslowerthanthenormalpregnancygroupTheHp

7、amRNAexpressioninpatientswithnormalvilliwashigherthanthepatientswithpregnancy—inducedhypertensionbyReal—timePCR(P001)ConclusionInthepregnancy——inducedhypertensiontheheparanaseexpressionWasde—creasedandtrophoblastinvasion