復(fù)凝聚法制備仿中藥成分微膠囊及其應(yīng)用.pdf

1、原創(chuàng)性聲明本人鄭重聲明：所呈交的學(xué)位論文，是本人在導(dǎo)師的指導(dǎo)下，獨(dú)立進(jìn)行研究工作所取得的成果。除文中已經(jīng)注明引用的內(nèi)容外，本論文不含任何其它個(gè)人或集體已經(jīng)發(fā)表或撰寫過的作品成果。對本文的研究做出重要貢獻(xiàn)的個(gè)人和集體，均己在文中以明確方式標(biāo)明。本人完全意識到本聲明的法律結(jié)果由本人承擔(dān)。學(xué)位論文作者簽名：狄旁簽字日期：懈卜月石日學(xué)位論文版權(quán)使用授權(quán)書學(xué)位論文作者完全了解北京服裝學(xué)院有關(guān)保留和使用學(xué)位論文的規(guī)定，即：研究生在校攻讀學(xué)位期間論文

2、工作的知識產(chǎn)權(quán)單位屬北京服裝學(xué)院。學(xué)校有權(quán)保留并向國家有關(guān)部門或機(jī)構(gòu)送交論文的復(fù)印件和磁盤，允許學(xué)位論文被查閱和借閱；學(xué)?？梢怨紝W(xué)位論文的全部或部分內(nèi)答，可以允許采用影印、縮印或其它復(fù)制手段保存、匯編學(xué)位論文。(保密的學(xué)位論文在解密后適用本授權(quán)書)學(xué)位論文作者簽名：夯畝導(dǎo)師簽名：維面彳簽字日期：糾羅年彥月廠同簽字日期：捌；年7L月／H學(xué)位論文作者畢業(yè)后去向：工作單位：通訊地址：日期：年月同月訊緘年電郵期●_lPRE凇佃0NANDAPP

3、LICATl0NOFMICR0CAPSULESOFIMll盼TIONHERBALINGREDIENTSBYCOMPLEXCOACERⅥATl0NAbstractBreasthyperplasiawasthehighestincidenceofbreastdisease，inseverecasescancausebJ‘castcancerHowtopreventbreasthyperplasiawasparticularlyimporta

4、ntIfyoucoundmicrocapsuleofactivepharmaceuticalingredientsthathadslowreleasefunctionandorganizedintoclothing，SothatpeoplewouldbeabletopreventionbreasthyperplasiawhenwearingtheclothingAccordingtopreliminaryresearchproject【

5、1|，molecularembeddingmethodandc(nplexcoacervationweremoresuitableformicrocapsuleofimitationherbalingredientsMolecularembeddingmethodsimplethancomplexcoacervationbutObtainaverylowcorec()lflcnt，lesspracticalvalueTherefore，

6、inthispaperchoosecomplexcoacervationformicrocapsulesSelectoleicacid(10wpolarcomponent)andtheBsitosterol(polarcomponent)asacorematerial，Gelatin／gumarabicmicrocapsulespreparedforthewallmaterialmainresearchpparationandfinis

7、hingprocessofmicrocapsulesOleicacidasthecoremateria，hindertheoptimalconditionssuchastheconcentrationof“vailmaterialWaS4％，theratioofcoreandwallmaterialswas1：1，pHvaluewas415425，undertheoptimalcondition：thecontentofthecorem

8、aterialwas4231％，theembeddingratew：ls4799％Whencuredbyglutal。aldehyde，micro—capsuleswasbrown，toxicityandinfluentialonsubsequentfinishingCuredbytransglutaminaseundetheoptimalconditionssuchastheratiooftmnsglutaminase(TG)andt

9、hegelatinwas02g／g，curingtemperaturewas45℃，curingtimewas8hPreparationtwokfiadsofmicrocapsulesrespectivelyglutaraldehydeandtransglutaminaseascuringagentforanalysiselectronmicroscopyparticlesize，heatreleaseproperties，infrar

10、edspectroscopythermalgravimetric，etcThenputthemfinishingthefabricforcomparisonthepropertiesofwhiteness，burstingstrengthandairpermeabilitymoisturepermeabilityBsitosterolasacorematerial，theoptimizationoftheemulsificationpr