全胃聯(lián)合脾切除治療進展期胃癌的系統(tǒng)評價.pdf

1、蘭州大學碩士學位論文全胃聯(lián)合脾切除治療進展期胃癌的系統(tǒng)評價姓名：李鵬申請學位級別：碩士專業(yè)：外科學（普通外科）指導教師：何曉東20090501蘭州人學碩上學位論文Abstractobjec廿Ve：1’0舔se豁theefficacy觚dsafctyoftotalgastrcctomysplenectomy(TGS)Ver鯽stotalgastrectomy(1’G)inpatientswithadv鋤cedgastriccarCi∞m弱

2、Methods：WbsearChedPubMed，Embaseo鼬raneLib刪嘎ChjneseBiomedicineDatabase，ChinaJoumaJFuUtextDatabase，ChineseScientificJoumalsFulltextDatabase鋤dhandsearched∞merelatedR鋤domized(bntrolledTrialsaboutTGS觚dTGtocIlreadv柚cedgastricca

3、rcinomaS，thequalityofmcludedstudiesw弱勰se豁edacC0rdiIlgt011leCOcllr鋤eSystematicReVie、ⅣSMethod柚dstatistical鋤alysiswasperfb加edbyReVMan4210∞fI、ⅣarcIksults：TIⅣ0RandomizecontrolledtrialsiIlvolVing394patientsmettheinclusioncrite

4、ria√蛆lthestlldiesmentionedmethodofIandomizationbutdidn’tdescI伯etheuseofblinding鋤dallocatedconcealment11lebaselineoftheincludedstlldyiscomparableTheMeta卸alysisshowedthat：therearc∞statiSticallydifferencesbe附eenthe鉚ogroupsi

5、n1，3，5一yearsurviValrate【0R(95％CI)098(061，158)，141(095，210)，129(086，129)respectiVely】鋤dcomplications【0R(95％CI)170(093，309)】11le化硪noobViouslydifferencesbe咐eenthet、Ⅳo罟即upsinoperatiVemonality，phymatologydirectioIls，reoperati

6、onnte，me齟operationtimeandaVeragedurationofhospitalstayConcIusio酗：111is咖dysugg：estsTGSsliglltlyincreascdin脅edcomplications觚dw觴notsuperiort0TGonsurviValrate，without蜘ingoperatiVemonalitySosplenedomyiIladV加ccdg硒triccarCinom弱

7、patientSwh0hadrcceiVedtotalg弱仃ectomyshouldgcnemllybeaVoided蛐l(wèi)e鯔canccrmetastatistospIeenorinordertothorougmyclearawaypositiVelymphoidⅡ0deillhilumandarteriosust11lncusofspleenBecause0fliteraturesamplesizeisless，theystillne