中國(guó)銀屑病患者白介素-20基因多態(tài)性和臨床表型分析.pdf

1、上海交通大學(xué)碩士學(xué)位論文中國(guó)銀屑病患者白介素-20基因多態(tài)性和臨床表型分析姓名：陳穎煒申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：皮膚病與性病學(xué)指導(dǎo)教師：鄭捷;羅邦國(guó)20080401上海交通大學(xué) 2005 級(jí)碩士學(xué)位論文 5ANALYSIS OF INTERLEUKIN-20 GENE POLYMORPHISM AND CLINICAL CHARACTERISTICS IN CHINESE PATIENTS WITH PSORIASIS VULGARIS

2、ABSTRACT Objective: To study the single nucleotide polymorphism (SNP) in promoter region of interleukin-20 (IL-20) gene and clinical characteristics in Chinese patients with psoriasis vulgaris. Methods: The clinical in

3、formation from the patients with psoriasis vulgaris were collected and IL-20 rs1713239 C>G polymorphism were genotyped. The association between clinical information and IL-20 genotype was assessed. Results: (1)The ge

4、notype distribution and the alleles frequency of IL-20 SNP were statistically different between the psoriatic patients and normal controls(P<0.05 and P<0.01, respectively). (2)There was statistically difference bet