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1、山西醫(yī)科大學(xué)碩士學(xué)位論文兒童抽動(dòng)障礙與A族溶血性鏈球菌感染關(guān)系的研究姓名:劉雅靜申請(qǐng)學(xué)位級(jí)別:碩士專業(yè):兒科學(xué)指導(dǎo)教師:都萍20060516斷睦科大學(xué)碩:h學(xué)位嗆文ThestudyofrelationshipofGroupAhemolyticstreptococcal’、1infectionandticdisordersAbstractobjective:Ticdisordersisakindofneuropsychiatricdise
2、asewithevidenthereditarytendencyManypatientshavebeenfoundinpubertyTheetiologyandpathogenesisofthisdisordersisunknownAsoneofenvironmentalfactors,GroupAstreptococcalinfectionalwaysplayanimportantroleinseveralyearsBecausema
3、nyfactorscanleadtoticdisorders,thisstudyaimedatexploringitsanti—DNaseBantibodies,tumornecrosisfactor旺(TNFa)tpersonnality,infectionhistory,mother’Spregnancy,parentalteachingpatternsandfamilysurroundinginformations,approch
4、ingdeeplyitspathogenesisandprovidingreasonabletreatmentplanforclinicalinterventionMethod:Fortypatientswithticdisordersand32age—matchedcontrolsubjectsparticipatedinacasecontrolexperimentalstudyThesesubjectsaremeasuredlabo
5、ratoryindexincludinganti—DNaseBantibodies,tumornecrosisfactora(TNF—ct)inbloodandquestionnaireaboutticdiordersriskyfactorsThedataiscollectedandanalysedwithSPSS120statisticalsoftsystemResults:Incasegroup,antiDNaseBantibodi
6、estitreandabsorbencyofTNFⅡissignificantlyhigherthanincontrolgroupTicdisordersriskyfactorsquestionnaireindicatesthatthereare7factorswhichhassignificantdifferencebetweenthecasegroupandthecontrolgroupThe7factorsarephysicalp
7、unishment,malnutritionduringpregnancy,children’Smild,children’Sselfwilledandbadtemperchildren’SattentiondeficitwithhyperactivityfeelingserioustensionrecentlysymptomofgroupAstreptococcalinfectionOccursintwoweeksbeforedeve
8、lopingticdisordersSinglefactorlogisticregressionanalysisrevealedthatthefollowingfactorsph)rsicalpunishment,malnutritionduringpregnancy,children’Smild,children’Sselfwilledandbadtemperchildren’Sattentiondeficitwithhyperact
9、ivityfeelingserioustensionrecentlyhavesignificantdifferenceMultifactorlogisticregressionanalysisindicatedthatfeelingserioustensionrecentlyisthemostriskyfactorsPartialcorrelationsanalysisindicatedapositivecorrelationbetwe
10、enanti—DNaseBantibodies,TNFc【andthescoreofYGTSSConclusion:TicdisordersispossiblyconcemedwithstreptococcalinfectionPhysicalpunishment,malnutritionduringpregnancy,children’Sselfwilledandbadtemperchildren’Sattentiondeficitw
11、it1hyperactivityfeelingserioustensionrecentlywouldbetheriskyfactorswhichleadtoticdisordersAmongthesefactorsfeelingserioustensionrecentlyisthemostriskyfactorsAndmildpersonalityispossiblyprotectivefactorKeyWords:Ticdisorde
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