274例新生兒壞死性小腸結腸炎臨床分析.pdf

1、獨 創(chuàng) 性 聲 明本人聲明所呈交的學位論文是本人在導師指導下進行的研究工作及取得的研究成果。除了文中特別加以標注和致謝的地方外，論文中不包含其他人已經(jīng)發(fā)表或撰寫過的研究成果，也不包含為獲得 暨南大學 暨南大學 或其他教育機構的學位或證書而使用過的材料。與我一同工作的同志對本研究所做的任何貢獻均已在論文中作了明確的說明并表示謝意。學位論文作者簽名：米沛明 米沛明 簽字日期： 2016 2016 年 06 06 月 24 24 日學位論文版

2、權使用授權書 學位論文版權使用授權書本學位論文作者完全了解 暨南大學 暨南大學 有關保留、使用學位論文的規(guī)定，有權保留并向國家有關部門或機構送交論文的復印件和磁盤， 允許論文被查閱和借閱。本人授權 暨南大學 南大學 可以將學位論文的全部或部分內容編入有關數(shù)據(jù)庫進行檢索，可以采用影印、縮印或掃描等復制手段保存、匯編學位論文。（保密的學位論文在解密后適用本授權書）學位論文作者簽名：米沛明 導師簽名：簽字日期：2016 年 06 月 24 日

3、 簽字日期： 年 月 日學位論文作者畢業(yè)后去向：工作工作單位： 清遠市婦幼保健院 電話：13750106716通訊地址：清遠市曙光二路 22 號 郵編：511500暨南大學碩士學位論文IIA clinical analysis of 274 cases of neonatalnecrotizing enterocolitisAbstractObjective: To explore the influencing factors of

4、neonatal necrotizing enterocolitis(NEC) and to provide theoretical basis for its early intervention.Methods: Incorporated in January 2008 to December 2012 12 hospitals in Pearl River Delta,northern Guangdong, western Gua

5、ngdong general hospital and maternal and child health careinstitute hospitalized children with NEC 274 cases were retrospectively analyzed, questionnairedesign, on the general situation, pregnancy, birth history, classif

6、ication of newborn, prior to the onsetof the illness, NEC clinical manifestations, feeding status, discharge diagnosis, and ending in theaspects of recording and analysis, premature and full-term infants groups were comp

7、ared, andaccording to the prognosis for cure group and worsening group of factors related to the multi factorLogistic regression analysis.Results: 1.The pathogenesis characteristics: all patients with ethnic Han national

8、ity, including 164cases (59.85%) of male and 110 cases (40.15%) of female, 177 cases (64.59%) of prematureinfants;in throughout the neonatal period range have the disease, which within 10 days after theonset of have 212

9、cases (77.37%).2.Cure group and contrast group deterioration: NEC cure groupand the deterioration of the group of single factor comparison: shock, staging, milk speed, milk time,non nutritive sucking, and gestational age

10、 of the corresponding P values were less than 0.05, withstatistical significance. Comparison of NEC in preterm and term infants, preterm infants appearpreeclampsia, premature rupture of membranes, PDA, metabolic acidosis

11、, plasma, red cells,,frequent episodes, NRDS, anemia, hyperbilirubinemia is significantly higher than that of full-terminfants of apnea, the difference was statistically significant (P < 0.05)).3.Multivariate logistic

12、regression analysis showed: shock, staging, milk speed are the risk factors influencing the prognosisof NEC, PDA, with milk speed are the risk factors influencing the prognosis of NEC in preterminfants, fed with formula

13、milk and milk speed is the risk factors affecting the prognosis of full-terminfants NEC; milk time, non nutritive sucking, gestational age is the protective factors of influencingthe prognosis of NEC, non nutritive sucki