Notch2陽性胰腺癌干樣細(xì)胞的特性及其與泡心細(xì)胞的相關(guān)性研究.pdf

1、Notch2陽性胰腺癌干樣細(xì)胞的特性及其與泡心細(xì)胞的相關(guān)性研究AstudyOilthecharacteristicsofNotch2positivepancreaticcancerstemiikecelisandthe1●‘●1●11reJatlonshlDW1thCentroaclnarce上Js姓名：周竹超指導(dǎo)教師：倪泉興教授導(dǎo)師小組：董強(qiáng)剛教授傅德良教授金忱教授完成日期：2011年9月1日復(fù)旦大學(xué)博士畢業(yè)論文CSC4—0ctADM

2、AKTALDHAPPAQPbHLHBMKlBSACACCCK8CK7DMEMDMSOEEDTAEGFEMTERKESCFCMFCSFGF10GAPGEMGSK3HEhECSsICsoIFUl主要英文縮略詞表cancerstemceI|soctamerbindingtranscriptionfactor4acinar—ductalmetaplasiaserinethreoninekinasealdehydedehydrogenaseamy

3、loidprecursorproteinaquaporinbasichelixloophelixbigMAPkinasebovineserumalbumincentrOacinarcellscelIcountkit8cytokeratin一7Dulbecc07SModifiedEagle’SMediumdimethylsulfoxideembryoethylenediaminetetraaceticacidepidermalgrowth

4、factorepithelialmesenchymaltransitionextracellularsignal—regulatedkinasesembryonicstemcellsflowcytometryfetalcalfserumfibroblastgrowthfactort0GTPaseactivationproteingemcitabineglycogensynthasekinase一3hematoxylinandeosinh

5、umanembryonicstemcellshalfmaximalinhibitoryconcentrationinsulinupstreamfactor1—2一癌干細(xì)胞八聚體結(jié)合轉(zhuǎn)錄因子4腺泡導(dǎo)管化生絲氨酸／蘇氨酸激酶醛脫氫酶淀粉樣前體蛋白水通道蛋白堿性螺旋。環(huán)螺旋大絲裂原活化蛋白激酶1牛血清白蛋白泡心細(xì)胞細(xì)胞計(jì)數(shù)試劑盒8細(xì)胞角蛋白7Dulbecco改良培養(yǎng)基二甲基亞砜胚胎乙二胺四乙酸表皮生長因子上皮間變細(xì)胞外信號調(diào)節(jié)蛋白激酶胚胎干細(xì)