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1、 博士學(xué)位論文法洛四聯(lián)癥患者 法洛四聯(lián)癥患者 Nkx2.5、ISLet1 和 MTHFR基因篩查 基因篩查 王琦光 學(xué) 號(hào) 1142008220 培 養(yǎng) 類(lèi) 別 全日制 學(xué) 位 類(lèi) 型 學(xué)術(shù)學(xué)位 一級(jí)學(xué)科(專(zhuān)業(yè)類(lèi)) 臨床醫(yī)學(xué) 二 級(jí) 學(xué) 科 ( 專(zhuān) 業(yè) ) 內(nèi)科學(xué)(心血管病學(xué)) 研 究 方 向 先天性心臟病與遺傳 指 導(dǎo) 教 師 朱鮮陽(yáng)教授(主任醫(yī)師) 培 養(yǎng) 單 位 第四軍醫(yī)大學(xué)第一附屬醫(yī)院 沈陽(yáng)軍區(qū)總醫(yī)院 二

2、O 一四年五月 分 類(lèi) 號(hào) R541.1 U D C 612.1 密 級(jí) 公開(kāi) 第 四 軍 醫(yī) 大 學(xué)The Fourth Military Medical University第四軍醫(yī)大學(xué)博士學(xué)位論文 目 錄 縮略語(yǔ)表 縮略語(yǔ)表················

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23、3;···· 22 第一部分 第一部分 TOF 患者 患者 NKX2.5,ISLET 1 和 MTHFR 基因外顯子變異位點(diǎn)檢測(cè) 基因外顯子變異位點(diǎn)檢測(cè)····· 22 1 材料··············&#

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51、···················55 第三部分 第三部分 MTHFR 基因 基因 C.C1333T SNP 與 CHD 發(fā)病風(fēng)險(xiǎn)相關(guān)性研究 發(fā)病風(fēng)險(xiǎn)相關(guān)性研究·······

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