流式細(xì)胞術(shù)檢測胃癌手術(shù)前后腹腔沖洗液CEA的變化及意義.pdf

1、蘭州大學(xué)碩士學(xué)位論文流式細(xì)胞術(shù)檢測胃癌手術(shù)前后腹腔沖洗液CEA的變化及意義姓名：張賢坤申請學(xué)位級別：碩士專業(yè)：外科學(xué)（普通外科）指導(dǎo)教師：劉宏斌20090601蘭州大學(xué)碩I：學(xué)位論文ChangesofCEAdetectedbynowcytometryinpe—toneallavageaftergastrectomyanditsclinicaIsigni6canceAbstractObjectiVe1、1’oexplorearmthodf

2、orpredictingperitonealmicrometast硒isingaslriccarcinomapatients2、TbinVestigatetheeffectofgastrectomyongastriccancercellsinperitoneallaVagefluidftompatientswithgastriccancerMethodsPeritoneallaVagefluidf如m50patientswithgast

3、riccancerand9patientswithbenjglldiseaseswerecollectedbeforeandaftergatrectOmyt0detectcarcinoembryonicantigen(CEA)usingFCMneperitoneallavagecytologyexaminations(PLC)wereca丌iedoutbyHEstailling1ksults1、Amonf50casesOfgastric

4、cancer，thepositiVerate0fCEAinperit徹ealwashingswas46％(23／50)，whichwassi印ific柚tlyhi曲efthanthatofPLC20％(10／50)ThepositiVerateofCEAconcunentlyincreasedwiththedepthoftllmorinVasion，TNMsta舀ng，lymphnodemetastasis鋤dserosalinvolV

5、ementNoneofthe9patientswithbenigndiseaseswerepOsitiVe2、Thepre，aIldpostoperatiVeCEApositiVeratewas46％(23／50)and64％(32／50)，rcspectiVely，柚dtherewassi印ific孤tdifference(P005)Tllepre，andpostoperatiVePLCpositiveratewas20％(10胚0)

6、and36％(18／50)(P005)。ConcIusions1、T1ledetectionofCEAbyFCMservesbettertopredictpatientswhowilldeVelopperitonealmetaStasisandcancerrecurrence2、Gastrectomyincreasestheintraperitonealf詫ecancercells【l沁ywords】Flowcytometry；Gast