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1、北京中醫(yī)藥大學(xué)碩士學(xué)位論文忘憂安神湯治療抑郁癥的療效和癥候改善特點(diǎn)的臨床觀察姓名:季菲申請學(xué)位級別:碩士專業(yè):中醫(yī)內(nèi)科臨床指導(dǎo)教師:鄒憶懷20040501蘭苧塑苧!ABSTRACTDepressionakindofdiseasethatischaracterizedbypersistentandscriousdepressedmood,belongstoaffectivedisordersItsincidencerateisrising
2、withthedevelopmentofsocietyandthechangeofthelifestyleIthasbecomeoneofthemaindiseasesthatharmthehumanphysicalandmentalhealthTheinvestigationofmodemmedicinehasprovedthatthereasonsandthepathogenesisofthediseaseareSOcomplext
3、hattheyarerelatedtomultiplefactorssuchasbiologypsychologyandsocietyManyproblemsaboutitarestillunknownSyntheticantidepressantsthatarecommonlyusedinmodemclinicaltreatmentaresurelyusefulbuttheyalsohavesomeflawsincludingnume
4、rousilleffectsandfrequentrelapseInrecentyearsmanyresearchersbegintopaymoreattentiontothosenaturalmedicines,includingTraditionalChineseMedicine(TCM)DepressionisdescribedasakindofgloomysyndromeinTCMTraditionalChineseMedici
5、nehasknownitforalongtimeandhasacompletetheoreticalsystemandalOtoftherapyexperiencesaboutitTCMhassomeadvantagesandpotentialitiesinthetreatmentofdepressionSoitsverynecessarytofindouttheclinicaleffectandcharacterofTCMtreatm
6、ent,includingtheeffectivetimeandchangesofthesymptomofTCMSummarizingandevaluatingtheclinicalresearchwithscientificmethodinordertoguidetheclinicaluseandfurtherstudyofTCMtreatmentismeaningfulThisresearchisdoneforthereasonsa
7、boveTwentydepressionpatientsaredividedInto2groupsinrandominthisstudy10inChinesedruggroup10inwesternmedicinegroupThefirstgroupistreatedbyWangyouAnshenTang(WATforshort),theothergroupistreatedbyDailixinThetreatmentlastsfor4
8、weeksThediagnosiscriteriaaredefinedaccordingtoCCMD一3criteriafordepressionandthediagnosiscriteriaaboutstagnationofliverqianddeficiencyofthespleenofthedepressedcycleofBipolardepressionestablishedbyChineseAssociationofInteg
9、ratedTraditionalandWesternMedicinein1991TheacceptedcriteriaaredefinedbyreferringtoHAMD17Inpretreatmentandeachweekinposttreatment,thetwogroupsareassessedbyHAMDinordertOgettheeffectandeffectivetimeofthetreatment,andevaluat
10、echangesofsymptomsofTCM,thelevelofT3,T4,TSH,and3groupsofsymptomsofdepressionthatarecalledgroupofmaincharactermentalandphysicalTheclinicalresearchshowsinWATgroup2ishealed,4haveobviouse腩ct3areeffectiveand1isuselessTheeffec
11、tiverateis90%4arehealed,3haveobviouseffect3areeffectiveand0isuselessinDailixingroupneeffectiverateis100%TheresultofHAMDshows,thetotalscoresofbothgroupsareremarkablelowerthanthatofpretreatmentafter1weekoftreatmentThereisn
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