靶向性重組人AIF分子對HER-2陽性腫瘤細(xì)胞的殺傷作用研究.pdf

1、第四軍醫(yī)大學(xué)博士學(xué)位論文靶向性重組人AIF分子對HER2陽性腫瘤細(xì)胞的殺傷作用研究姓名：于翠娟申請學(xué)位級別：博士專業(yè)：生物化學(xué)與分子生物學(xué)指導(dǎo)教師：楊安鋼王成濟(jì)2003.4.1AFPAIFAmf1AcinusBHCAD英文縮略語表d—fetoproteinapoptosisinducingfactorapoptoticproteaseactivatingfactor一1apoptoticchromatincondensationindu

2、cerintllenucleusBcl2homologydomaincaspaseactivateddeoxyribonucleasecaspasecysteinylaspartatespecificproteaseCDcytosinedeaminaseCEAcarcinoembryonicantigenCTLcytotoxinTlymphocyteCytCcytochromecDFF45DNAfragmentationfactor一4

3、5DNAPKDNAdependentproteinkinaseDTdiphtheriatoxinEF2elongationfactor2ELISAenzyme—linkedimmunosorbantassayEndoGendonucleaseGFADflavinadeninedinucleotideGCVgancyclovirGFPgreenfluorescenceproteinGMCSFgranulocyteandmacrophage

4、colonystimulatingfactorGRglutathionereductaseGrBgranzymeBHSVtkherpessimplexvirusthymidinekinase1甲胎蛋白凋亡誘導(dǎo)因子凋亡蛋白酶激活因子I核凋亡染色質(zhì)固縮誘導(dǎo)分子Bcl2同源結(jié)構(gòu)域caspase活化的脫氧核糖核酸酶天冬氨酸特異性半胱氨酸蛋白酶胞嘧啶脫氨酶癌胚抗原細(xì)胞毒性T淋巴細(xì)胞細(xì)胞色素cDNA片段化因子45DNA依賴的蛋白激酶白喉毒素(蛋白質(zhì)